梁國才 上海市第八人民醫院（上海，200235，中國）
摘要 目的 研究觀察麝香保心丸（簡稱HMP）長期治療冠心病心肌梗死的臨床療效。方法 從700例冠心病患者中選擇60例發生心肌梗死後由于經濟或心理原因不願或拒絕進行冠脉介入治療或冠脉搭橋術的患者，隨機分成治療組和對照組。其中30例長期口服或舌下含HMP2丸/次，每日3次爲治療組；不長期用或不用HMP的30例爲對照組。結果 治療組30例心肌梗死後長期應用HMP1～7年以上的患者生存已達5～14年以上，有1例于8年後死亡，生存率爲96.7%。對照組30例心肌梗死後不長期服用或不用HMP的患者生存已達2～12年以上，有4例于2～4年死亡，生存率爲86.7%。二組差异十分明顯（P<0.01）。結論 冠心病心肌梗死後長期用HMP治療組在防治心絞痛、心肌梗死再發、心功能改善、生活質量提高和生存率方面明顯優于不長期用或不用HMP的對照組。
關鍵詞 麝香保心丸 冠心病 心肌梗死 長期治療
Clinical study in long-term therapy with heart-protected musk pill for myocardial infarction of coronary heart disease
LIANG Guocai.Shanghai No.8 people's hospital(Shanghai,200235,China)
Abstract Objective To study the clinical effects of Shexiang Baoxin pill in long-term treating myocardial infarction of coronary heart disease.Methods Group 1 (treatment group),the 30 patients was long-term treated with Shexiang Baoxin pill 2 pill,3 times daily.Group 2 (control group),the 30 patients was not long-term or not treated with Shexiang Baoxin pill.Results Group 1 survial rate of 96.7% was better than Group 2 survial rate of 86.7% in the therapecctic effect and there was significant difference between group 1 and group 2 (p<0.01).Conclusion The effects on myocardial ingarction of coronary heart disease treated by Shexiang Baoxin pill in long-term therapeutic effect was letter,satisfactory and can protect the vascular endothelial cell,improve the myocardial blood supply,reduce the occurrence of angina pectoris,decrease the area of myocardial infarction and promote the angiogenesis.
Keywords heart-protected musk pill(she xiang bao xin wan);coronary heart disease;myocardial infarction;long-term therapy
