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綫粒體ATP敏感性鉀離子通道與缺血預適應

 2008年06月24日 国际心血管杂志 字号设置:[ ]
馬建群 張蕾 濱州醫學院附屬醫院心血管內科(濱州,256603,中國)
Mitochondrial ATP- sensitive potassium channel and ischemic preconditioning
MA Jianqun, ZHANG Lei. The affiliated hospital of Binzhou medical college(Binzhou, 256603,China)
摘要  心肌缺血預適應是心肌缺血-再灌注損傷最有力的一種保護反應,綫粒體ATP敏感性鉀通道是介導預適應保護作用的重要環節,本文對綫粒體ATP敏感性鉀離子通道介導缺血預適應的心臟保護機制做一綜述。
關鍵詞  綫粒體 ATP敏感性鉀離子通道 缺血預適應
Abstract  Myocardial Ischemic Preconditioning is a protection of the most powerful reaction of myocardial ischemia-reperfusion injury. A mitochondrial ATP-sensitive potassium channel is an important link which mediated the protective effect of preconditioning. This article lies to the protection machine concerning mitochondrial ATP-sensitive potassium channels- mediated ischemic preconditioning heart protection machine make summary.
Keywords  mitochondrion; ATP- sensitive potassium channel;ischemic preconditioning